Many New Methods Of Diabetes Treatment

Experts have long suggested that diabetes is a "source of sickness" in a variety of chronic disease, most patients with diabetes is painful.
According to the Ministry of Health survey, China now has at least 34 million people with diabetes, accounting for 2.6% of the total population.

And 30 years ago, this figure was only 0.7%. According to the World Health Organization predicts that by 2025 the world will have 300 million diabetes patients, while China is likely to become diabetic, "superpower."

Experts have long suggested that diabetes is a "source of sickness" in a variety of chronic disease, most patients with diabetes is painful. In order to sustain life, the patient can not do without daily insulin and drugs; because the body lacks insulin or the body can not use insulin, patients are often hesitant to eat, just moving, always worried about blood sugar, life-threatening; In addition, Diabetes also affects the blood vessels and nervous system, causing high blood pressure, stroke and other diseases --- say, diabetes, human life becomes fragile.

Great harm because of diabetes, the incidence of more serious, therefore, overcome diabetes, make life easier for diabetes patients, has been the focus of the international medical community. Conquest of diabetes in the end how long? With this issue, the domestic newspaper reporter interviewed the field of diabetes research and treatment of several experts, meanwhile, told reporters in Denmark and in diabetes research is a global leader in contact Novo Nordisk, interviewed the the company's vice president and chief scientific officer Maizi hole Sigma Dr. Tang Musen.

Drug: control blood sugar more "intelligent"

In Copenhagen in Denmark, Novo Nordisk headquarters, reporters saw Dr. Tang Musen. He is a quick thinking, and often people can not keep pace, a diabetes expert. Interview, he described to reporters on the road in the conquest of diabetes, scientists have made the latest developments.

Dr. Tang Musen told reporters that people with diabetes to get rid of one of the biggest worry is not insulin dependent, therefore, scientists have been working on how to reduce the number of diabetes drugs, while increasing the drug's safety. He said that recently, called glucagon-like peptide-1 natural hormone has been of great concern to the medical profession, the use of this material, we can develop a more secure, convenient diabetes drugs. He told reporters that the body has called glucagon substances will stimulate glycogenolysis, elevated blood glucose levels. In eating, gut will release glucagon-like peptide-1. On the one hand an effect on the brain to reduce appetite; on the one hand to stimulate the body to secrete insulin, suppress glucagon, lower blood sugar.

Dr. Tang Musen that processed glucagon-like peptide-1 in the human body 24 hours to take effect, as long as the higher than normal blood sugar levels, it can be mobilized, "suppress" blood sugar. Moreover, compared to insulin injections and taking glucagon-like peptide-1 drugs can blood sugar dropped to normal levels, then medication will no longer have an effect; the insulin dose must be carefully controlled, because excessive doses, will lead to low blood sugar, severe life-threatening. Obesity is the cause of type 2 diabetes is an important factor, and glucagon-like peptide-1 can suppress appetite, is also beneficial to weight loss. Dr. Thomson, if successful, glucagon-like peptide-1 drug

Materials will be available this winter for the third clinical trial. In addition, the reporter also learned that some new drugs will focus placed to help patients get rid of the pain of the injection needle. Indian experts have developed an oral medication, insulin will be put into the capsule until the intestine was released. In addition, scientists have also developed a package of insulin, patients can "suck" the way insulin intake. It is reported that the drug will be available this year.

Surgery: cell transplantation for patients to get rid of insulin

In addition to actively develop new drugs, through surgery and other aspects of diabetes, scientists have made no small achievement. According to the British Broadcasting Corporation (BBC) reported that from last September to the end of January this year, Britain's 61-year-old named Ryan with type 1 diabetes received three transplants of islet β-cells. Now, in addition to taking anti-rejection drugs regularly, he has no need to inject insulin up. He said: "I feel like a changed man." King's College London Medical experts believe that for type 1 diabetes, this is an exciting news. It is reported that Japan, Canada and other countries have carried out such transplant. Among them, Japan's transplant patient, a woman the mother of islet β cells, 22 days after surgery to get rid of insulin.

Dr. Tang Musen also mentioned that Novo Nordisk is studying artificial pancreas. Artificial pancreas is mounted in the body of a tiny device, real-time detection of blood glucose levels, insulin and then release the test results for patients, convenient and timely. Dr. Tang Musen optimistic that these results will greatly improve the lives of patients with diabetes. Reporters also learned that scientists at the University of California, is also studying artificial pancreas.

Early diagnosis: The new method greatly improves the detection rate

Diabetes treatment in continuous improvement, while early detection of diabetes have also been everyone's attention. Reporters from the Beijing Tongren Hospital, Division of physician medical cadres learned Zhou Jian, about 80% of diabetes patients is found in the examination, to identify the problems, many people have been very ill the. He believes that this figure adequately illustrates the importance of early diagnosis. Shanghai Diabetes Institute, Professor Jia Weiping told reporters: "There are about 50% of diabetes patients appears quite normal, ruddy, so easily, if you go to the hospital for tests, it may not even know they have disease, and naturally not take treatment. "

Diabetes screening is currently the major comprehensive survey of fasting and postprandial blood glucose, and then make a diagnosis. Duke University researchers have invented a name HgA1c the early diagnosis of type 2 diabetes, the body by detecting the six weeks the average blood glucose level to screen for diabetes, to improve the detection accuracy. They are at high risk of 1235 subjects were examined and found that 4.5% of people with diabetes, the final detection rate of 75%, while the use of traditional screening methods, many patients have shown "no disease."

In addition to HgA1c detection, scientific director of the South African Medical Research Council also invented a type 2 diabetes detection: determination of blood insulin and insulin in the ratio of the former. Before the insulin is a protein secreted by the pancreas, can be converted into insulin, but patients with type 2 diabetes before insulin but does not become insulin. Therefore, by detecting the ratio of two substances, can be found in diabetes.

Even decades to conquer diabetes

With so many drugs, surgery and diagnostic methods, then, to conquer diabetes, the most fundamental way? Dr. Tang Musen that the cure for this disease hope in stem cells. "Stem cells can grow into any cell." He told reporters, can stem cells into insulin-producing islet β-cells should only be a matter of time, the key now is to find the transformation method. He pointed out that to complete the stem cells into pancreatic islet β-cell research, takes about 20 years, they need to conduct clinical trials for 10 years, that is, to cure diabetes, have to wait two or three decades. He told reporters that for now, type 2 diabetes are most likely to be the first radical. Reporters from the Chinese experts on diabetes research, Chinese Medical Diabetes Society chairman Kun-san Xiang learned academicians of China's diabetes patients, 85% of people suffering from type 2 diabetes. Thus, Thomson predicted Dr. diabetic patients in China is undoubtedly a blessing.

In addition to stem cells, gene therapy is currently the focus of global concern. Item academician told reporters that China had approximately 5% of patients with diabetes have a special type of diabetes. Diabetes is the body of this one gene, "bad" result, also called single-gene mutation diabetes. Now, the international community have it as a breakthrough in the study, the problems caused by a single gene through diabetes research, and multiple genes causing type 2 diabetes also have conquered hope.

In addition, the reporter also learned that foreign scientists are studying diabetes vaccine. Recently, King's College London University of Bristol, prepared jointly with the world's first human trials of type 1 diabetes vaccine. This vaccine into the blood, it will produce a protective cell, blocking β-cell destruction of the white blood cells. If successful, diabetes research will a big step forward.

Chinese people prone to diabetes than Westerners

Although diabetes is a worldwide topic, but Dr. Tang Musen that Chinese people pay particular attention to prevention and treatment of diabetes. He said that as East and West of the gene, the Chinese are more likely to suffer from diabetes. Americans to 30% of body weight is fat only when the risk of diabetes, while China may have 23% of body weight is fat, it has been suffering from a type 2 diabetes. In addition, he told reporters in China's rural areas, 2% -3% of people suffering from diabetes, the prevalence of Beijing and other places even close to 10%, and most patients did not receive good treatment. After 2030, the number of Chinese patients with diabetes may double to 70 million. Professor Jia Weiping pointed out that from the perspective of China's population distribution, family history of diabetes, more fat (especially the big belly, thin legs), people over 45 years of age in high risk groups. Mental and work pressure, more people are entertaining the incidence is relatively high.

Dr. Tang Musen told reporters, according to the survey, 58 percent of the global diabetes and obesity, in some countries, this ratio is as high as 90%. Now, many Chinese people who blindly follow the Western way of life: eat high-calorie foods, with car travel, the result more and more obese, the incidence of diabetes on the rise. He is not without concern that, in accepting the training of people to prevent diabetes, only 1/4-1/3 of the people will follow the guidance to improve their lives, therefore, have to carry on educational work. Professor Jia Weiping said that as long as people with diabetes take active and effective treatment, adhere to a healthy lifestyle, not only to live a happy life, but also longevity.