Monday, June 20, 2011

Diabetes Drug Treatment Process Errors

Misunderstanding: "There where the three-drug", hyperglycemia refuse medication
Diet therapy is an important means of treatment of diabetes, but diet alone can only make part of the mild patients achieved satisfactory glycemic control for most patients to drug treatment only provides a foundation. So for those who diet alone can not achieve treatment goals in diabetic patients, must be added with the proper medication. But the same can not be relaxed after treatment diet, we can say diet, exercise and drugs is an organic unity, which constitutes the treatment of diabetes, "Troika." In general, the dose of hypoglycemic drug side effects are mild, it is safe to take. Furthermore, if the blood glucose control can not be satisfied, "high blood glucose toxicity" caused harm to the body far more than the side effects of hypoglycemic agents, so that more harm than good.
Myth: high cost of medicines, blood glucose must be good
Currently on the market more types of oral hypoglycemic drugs, the prices vary, many patients with diabetes seem to have the mind of such a "consensus": the more expensive the price of drugs hypoglycemic effect is more obvious, than imported drugs must be made good . In fact, this view is one-sided, drug prices can not serve as the basis for drug selection should be based on each patient's own disease states may be different.
Insulin secretion and insulin resistance is the body of the two aspects of diabetes, so oral hypoglycemic agents is the key to solve these two problems. Since each individual differences exist between patients, therefore, different patients need different types of antidiabetic drugs. In addition to have some knowledge of the drug, but also with diabetes age of onset, duration, height, weight and history of other diseases and other factors into account, can not simply choose the price up. Otherwise, not only unsatisfactory glycemic control, may also damage the body's other organs. So, you have to choose a specialist under the guidance of hypoglycemic drugs.
Myth: Drug frequent change, combined with random
Many patients believe that taking a hypoglycemic drugs poor blood sugar control, the combined use of one, two, if still not standard on the three kinds or four kinds of oral hypoglycemic drugs taken together in order to achieve a "cumulative effect" . This idea is not comprehensive, not clear and specific types of drug interactions, blindly increasing the oral medication, may not only fail to increase the efficacy of the role, but will make the drug "side effects" to be cumulative.
Currently, the clinical application of the principles advocated drug combination is generally: between different drugs the same drugs at the same time to avoid the application; different types of drugs can be combined with two or three; insulin can be used with any kind with the use of oral hypoglycemic drugs . Different types of drugs hypoglycemic mechanisms, the combined efficacy can play a complementary role to play in different ways a greater hypoglycemic effect. For example, sulfonylurea drugs, primarily to promote insulin secretion, and biguanide drugs to promote tissue glucose utilization, increased insulin sensitivity, such a "two-pronged approach", can achieve a better hypoglycemic effect. With commonly used oral hypoglycemic drugs are: sulfonylurea + metformin, sulfonylurea + α-glucosidase inhibitor, sulfonylurea + thiazole TZDs, biguanides + α-glucosidase inhibitors, biguanides + thiazolidinediones, TZDs.
In addition, most oral hypoglycemic agents hypoglycemic effect is not immediate, in particular, α-glucosidase inhibitors, thiazolidinediones, TZDs and biguanide drugs, often take days or weeks in order to better play its role so often after treatment to observe a period of time. Frequent dressing changes, it is difficult to achieve the maximum hypoglycemic effect of the drug. Has been better control of patients with hypoglycemic agents not to be any changes, otherwise it will cause blood sugar fluctuations, and may even accelerate the failure of oral hypoglycemic agents.
Myth: "hit and will be addicted," refused to insulin
As we all know, insulin is hypoglycemic best weapon. However, many diabetic patients on insulin, there are many prejudices, and even after that insulin addiction, refused to insulin, lost the opportunity to treat serious complications. As the former medical profession has to type 2 diabetes referred to as "non-insulin-dependent diabetes mellitus", so that many patients with type 2 diabetes, insulin injections should not be. In fact, this understanding is not correct, in addition to type 1 diabetes, type 2 diabetes require insulin in the following circumstances: (1) The adequate treatment of oral hypoglycemic agents, blood glucose control were not satisfied; (2) acute complications; (3) with severe chronic complications; (4) with severe disease; (5) infection; (6), surgery and stress; (7) pregnancy and so on. Most of these cases is temporary use of insulin, even after the acute state to switch to oral medication to eliminate. And for those who had failed on oral hypoglycemic agents in patients using insulin for some time, while eliminating the high glucose toxicity; the other hand, allows pancreatic β-cell rest and recovery, may renew the islet β-cells of oral hypoglycemic drug reaction, then consider switching to oral hypoglycemic agents. Of course, if their β-cell function completely recession, the situation can not be removed or the merger, we need long-term insulin.
Myth: good blood glucose control, drug stopped immediately
Diabetes is a chronic metabolic disease, the medical profession at home and abroad this disease has no cure, good blood glucose control and maintenance of long-standing need for comprehensive treatment, including diet, exercise and medication. However, many patients tend to see their blood sugar to normal immediately after the relaxation of the diet, or even withdrawal. Restore normal blood glucose is a doctor and patient pursuit of the ideal goal should be to maintain normal blood glucose after the original treatment. If you suspect a low blood sugar reactions, can be appropriate under the guidance of a doctor to reduce the dosage. However, in elderly patients, or associated with a clear heart, brain, liver and kidney complications in patients with controlled blood sugar levels should not be too low. Each patient should consult a doctor to specialist, to develop a realistic glycemic goals.
Myth: As long as it feels good, do not have to find a doctor
Many diabetic patients in the treatment process, always thinks, as long as there is no obvious discomfort, he said that the condition under control, do not see a doctor, but does not check blood sugar, which is very risky. We know that the current diagnosis of diabetes and to determine the disease, based primarily on blood sugar levels, symptoms only as a reference. Many studies have shown that all the complications of diabetes, development, and blood glucose levels are closely related. Therefore, each patient must adhere to regular blood sugar testing, including fasting glucose, 2-hour postprandial blood glucose. General recommendations were more stable blood sugar, check every 2 to 4 weeks and a fasting 2-hour postprandial blood glucose, but for those in the treatment of blood glucose fluctuations or adjustments should be appropriate to increase the number of blood glucose testing. Of course, if patients have a portable self-blood glucose meter, blood glucose can be closely monitored daily. In addition, glycated hemoglobin reflects the past 2 to 3 months the overall level of blood sugar, generally require 3 to 6 months to once in order to more fully grasp the level of blood glucose control.
Finally, you need to remind the majority of patients, diabetes is both preventable and control of a class of diseases, it is important to take a scientific and rational method of treatment, in your perseverance. Through the joint efforts of you and your physician, I believe you will be able to enjoy the same life and health of people, the same longevity.

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