Journal of the American Medical Association "published a study claiming a breakthrough in diabetes treatment. Medical personnel in Brazil on 15 patients with type I stem cell transplantation experiments, the results are out of 13 insulin-dependent patients, but also without taking other drugs. The first experiments were not receiving injections of artificial insulin for 3 years.
As the two clinical types of diabetes, I diabetes is an autoimmune disease, is the body's immune system to insulin-producing cells within the pancreas as foreign cells caused their elimination. Type II diabetes, it is not as common, but patients must rely on insulin injections for life to sustain life.
One of the researchers at Northwestern University School of Medicine in Chicago, said Dr. Richard Burt, "This is the type I diabetes treatment to achieve such results the first time, patients do not have any medicine or any treatment, blood glucose levels remain normal."
The principle of stem cell transplantation
Diabetes has always been difficult to treat disease, the medical profession, the traditional method of treatment can only be a life-long medication or insulin, and the emergence of stem cells offers hope to people with diabetes, stem cell therapy for diabetes is the most cutting-edge treatment, can gradually recovered from the fundamental islet function, insulin to diabetic patients out of trouble!
Stem cells are the body of a class of self-renewal capacity and ability to produce differentiated cells of the original cells, in a suitable environment can replicate themselves and their own produce large amounts of the same cells can also differentiate into functional cells, resulting in the human body various types of cells needed for the system, tissues, organs, etc., stem cells are a "can do anything in the cell", the medical community known as the "million by cell."
Because stem cells this "wildcard" function, clinical stem cells by extracting, in the training room were cultured under appropriate conditions, amplified and induced to differentiate into the required stem cells, then extraction of the high quantity and quality of stem cells back to patients. Use of stem cells self-replication and differentiation potential to repair damaged cells and restore damaged organs and tissues of normal function. Another stem cell implantation, the use of stem cells homing effect automatically, the stem cells will be automatically transferred to the damaged body lesions, differentiation of various types of cells generate the required to achieve the restoration of human cells inherent in the system and restore system function, so that Patients with symptoms improved to the purpose of treatment.
Prospects need to study
Ensure safety is the fundamental
Stem cell transplantation for the potential risks of new therapies, it was questioned. For example, the potential hazards of stem cell transplantation include infertility and late-onset cancer. However, 15 patients received none of the experiment died, and no lasting side effects.
There are also many medical personnel have the prospect of stem cell therapy is very optimistic. "Journal of the American Medical Association," the editorial said, results are likely to trigger a new wave of enthusiasm, and ultimately help people prevent and cure diabetes.
However, in order to ensure the success rate of stem cell therapy and safety, the researchers also need to further study stem cell transplantation therapy to determine whether it is universal, as I diabetes therapy.
Experimental patients hospitalized 3 weeks
Burt said that they received the approval of the Brazilian Code of Ethics Committee, University of bone marrow in the center of Sao Paulo, Brazil carried out the experiment. The 15 subjects aged 14 to 31 years old, newly diagnosed type I diabetes soon. He said that this time is critical, because at this time in patients with insulin-producing cells in vivo has not been completely immune system damage.
Burt said that hospital patients before and after about 3 weeks time. Many patients in the experiment because of the side effects of therapy are nausea, vomiting and hair loss phenomenon. However, side effects did not last long.
Experimental procedure stem cell transplantation therapy
First stimulate the body to generate new stem cells in patients, from the blood to pick them out.
The patients were then high-dose chemotherapy for several days, prompting the immune system of patients stop working, so that the residual body to insulin-producing cells from the immune system "murderous."
Of course, in the immune system does not work, patients must be hospitalized and rely on potent drugs to stop the disease.
Then, the blood from the patient before the doctor extracted stem cells were injected back to the patient's body to form a new immune system. The new immune system will no longer attack the insulin-producing cells.
As the two clinical types of diabetes, I diabetes is an autoimmune disease, is the body's immune system to insulin-producing cells within the pancreas as foreign cells caused their elimination. Type II diabetes, it is not as common, but patients must rely on insulin injections for life to sustain life.
One of the researchers at Northwestern University School of Medicine in Chicago, said Dr. Richard Burt, "This is the type I diabetes treatment to achieve such results the first time, patients do not have any medicine or any treatment, blood glucose levels remain normal."
The principle of stem cell transplantation
Diabetes has always been difficult to treat disease, the medical profession, the traditional method of treatment can only be a life-long medication or insulin, and the emergence of stem cells offers hope to people with diabetes, stem cell therapy for diabetes is the most cutting-edge treatment, can gradually recovered from the fundamental islet function, insulin to diabetic patients out of trouble!
Stem cells are the body of a class of self-renewal capacity and ability to produce differentiated cells of the original cells, in a suitable environment can replicate themselves and their own produce large amounts of the same cells can also differentiate into functional cells, resulting in the human body various types of cells needed for the system, tissues, organs, etc., stem cells are a "can do anything in the cell", the medical community known as the "million by cell."
Because stem cells this "wildcard" function, clinical stem cells by extracting, in the training room were cultured under appropriate conditions, amplified and induced to differentiate into the required stem cells, then extraction of the high quantity and quality of stem cells back to patients. Use of stem cells self-replication and differentiation potential to repair damaged cells and restore damaged organs and tissues of normal function. Another stem cell implantation, the use of stem cells homing effect automatically, the stem cells will be automatically transferred to the damaged body lesions, differentiation of various types of cells generate the required to achieve the restoration of human cells inherent in the system and restore system function, so that Patients with symptoms improved to the purpose of treatment.
Prospects need to study
Ensure safety is the fundamental
Stem cell transplantation for the potential risks of new therapies, it was questioned. For example, the potential hazards of stem cell transplantation include infertility and late-onset cancer. However, 15 patients received none of the experiment died, and no lasting side effects.
There are also many medical personnel have the prospect of stem cell therapy is very optimistic. "Journal of the American Medical Association," the editorial said, results are likely to trigger a new wave of enthusiasm, and ultimately help people prevent and cure diabetes.
However, in order to ensure the success rate of stem cell therapy and safety, the researchers also need to further study stem cell transplantation therapy to determine whether it is universal, as I diabetes therapy.
Experimental patients hospitalized 3 weeks
Burt said that they received the approval of the Brazilian Code of Ethics Committee, University of bone marrow in the center of Sao Paulo, Brazil carried out the experiment. The 15 subjects aged 14 to 31 years old, newly diagnosed type I diabetes soon. He said that this time is critical, because at this time in patients with insulin-producing cells in vivo has not been completely immune system damage.
Burt said that hospital patients before and after about 3 weeks time. Many patients in the experiment because of the side effects of therapy are nausea, vomiting and hair loss phenomenon. However, side effects did not last long.
Experimental procedure stem cell transplantation therapy
First stimulate the body to generate new stem cells in patients, from the blood to pick them out.
The patients were then high-dose chemotherapy for several days, prompting the immune system of patients stop working, so that the residual body to insulin-producing cells from the immune system "murderous."
Of course, in the immune system does not work, patients must be hospitalized and rely on potent drugs to stop the disease.
Then, the blood from the patient before the doctor extracted stem cells were injected back to the patient's body to form a new immune system. The new immune system will no longer attack the insulin-producing cells.
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